What Is Myoglobin?
What it is
Myoglobin is a muscle protein released into blood when muscle — including heart muscle — is damaged.
Why it matters
It rises earliest after myocardial injury but has low cardiac specificity; used as an early marker in multi-marker panels.
Specimen
Whole blood / serum / plasma
Interpretation
Elevated = muscle (including cardiac) injury.
Limitations
Low cardiac specificity — use in panels with troponin.
Related test: Myoglobin Rapid Test — specimen: WB / S / P
Frequently Asked Questions
Is myoglobin cardiac-specific? No — it is an early but non-specific marker; use with troponin.
Related knowledge
References
- Thygesen K et al. 2019.
Last reviewed: 2026-09-12