What Is Procalcitonin (PCT)?
What it is
Procalcitonin is a precursor of calcitonin that rises markedly in systemic bacterial infection and sepsis, but much less in viral infection.
Why it matters
PCT helps distinguish bacterial from viral infection and guides antibiotic decisions.
Specimen
Whole blood / serum / plasma
Interpretation
Elevated = supports bacterial infection/sepsis; low = less likely bacterial.
Limitations
Supportive marker — interpret with clinical context; not a standalone diagnosis.
Related test: Procalcitonin Rapid Test — specimen: WB / S / P
Frequently Asked Questions
What does an elevated PCT indicate? It supports bacterial infection or sepsis — interpret with clinical context.
Related knowledge
References
- Procalcitonin-guided antibiotic stewardship guidance (clinical consensus).
Last reviewed: 2026-09-12